Introduction : Gallbladder paraganglioma is a very rare tumor and only a few cases have been reported so far.Most of these tumors are asymptomatic and confirmed incidentally after operation. The clinical significance of gallbladder paraganglioma is differential diagnosis with gallbladder cancer or other gallbladder tumor.

Methods : A 48-year-old woman presenting with intermittent abdominal pain. The laboratory tests were all within normal range including tumor marker.MRI showed8 cm sizedmass lesion in gallbladder body and fundus with low signal intensity in T2-weighted imagesconsidered as hemorrhage.We planned a laparoscopic cholecystectomy under the impression of gallbladder tumor with hemorrhage.

Results : We performed laparoscopic cholecystectomy successfully.In the gallbladder lumen, several black stonesless than 1cm in diameterand large hematomawere observed. And about 1 cm sized polypoid lesion was detected in the fundus. In microscopic examination of polypoid lesion showed cuboidal cells including granular cytoplasm surrounded by a fibrous septum containing blood vessels.The chief cell was nested in the inside and the spindle shape sustentacular cells surrounded by the Zellballen cellular arrangement. Synaptophysin, CD56, chromogranin staining were strongly positive for chief cells. In the histopathologic examinations, the diagnosis was gallbladder paraganglioma with hemorrhage.

Conclusions : Gallbladder paraganglioma is extremely rare tumor and usually diagnosed incidentally after operation. We need to aware of this disease entity for differentiation of this tumor with other gallbladder tumors.