Detailed Abstract
[BP Oral Presentation 3]
[BP OP 3-3] Risk Factors of Postoperative Pancreatic Fistula after Pancreaticoduodenectomy: A Multicenter Cohort Study
Huisong LEE1, Hyeon Kook LEE* 1, Seog-Ki MIN1, Hong Beom KIM2, Wooil KWON2, Jin-Young JANG2, Sun-Whe KIM2, Inwoong HAN3, Jin Seok HEO3, Seong Ho CHOI3, Dong Wook CHOI3, Koo Jeong KANG4, Sang Jae PARK5, Woo Jung LEE6, Hee Chul YU7, Soon-Chan HONG8, Yoo-Shi
1Surgery, Mokdong Hospital, Ewha Womans University College of Medicine, Korea
2Surgery, Seoul National University College of Medicine, Korea
3Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Korea
4Surgery, Keimyung University
Introduction : This study was designed to analyze the risk factors associated with postoperative pancreatic fistula (PF) using a large cohort registered in the Korean Tumor Registry System: Biliary-Pancreas (KOTUS-BP).
Methods : Sixty-two surgeons from 18 tertiary hospitals participated in the KOTUS-BP cohort. Patients who underwent pancreaticoduodenectomy for periampullary neoplasia were identified in the database. We analyzed the patients’ characteristics, preoperative data, operation method, and postoperative outcomes including PF.
Results : Of the 4,846 patients, 179 patients with missing records of PF were excluded. A total of 4,667 patients were enrolled in this study. Postoperatively, 298 patients (6.4%) had experienced clinically relevant pancreatic fistula (CR-PF). In multivariate analysis, female sex, pancreatic cancer, and lymphovascular invasion were statistically significantly protective factor of CR-PF (p = 0.006, p < 0.001, p = 0.039, respectively). However, pylorus preservation was associated with CR-PF (p <0.001).
Conclusions : The analysis of large-scale multicenter cohort data showed that female gender, pancreatic cancer, conventional pancreaticoduodenectomy, and lymphovascular invasion were associated with decreased CR-PF incidence.
Methods : Sixty-two surgeons from 18 tertiary hospitals participated in the KOTUS-BP cohort. Patients who underwent pancreaticoduodenectomy for periampullary neoplasia were identified in the database. We analyzed the patients’ characteristics, preoperative data, operation method, and postoperative outcomes including PF.
Results : Of the 4,846 patients, 179 patients with missing records of PF were excluded. A total of 4,667 patients were enrolled in this study. Postoperatively, 298 patients (6.4%) had experienced clinically relevant pancreatic fistula (CR-PF). In multivariate analysis, female sex, pancreatic cancer, and lymphovascular invasion were statistically significantly protective factor of CR-PF (p = 0.006, p < 0.001, p = 0.039, respectively). However, pylorus preservation was associated with CR-PF (p <0.001).
Conclusions : The analysis of large-scale multicenter cohort data showed that female gender, pancreatic cancer, conventional pancreaticoduodenectomy, and lymphovascular invasion were associated with decreased CR-PF incidence.
SESSION
BP Oral Presentation 3
Room C 4/5/2019 3:54 PM - 4:01 PM